Future research targeting the effects of hypoxemia on cognition controlling for other clinical factors in large groups of patients with OSA will be important. 1 Table of Content Uploaded by MikaGieJergoLariza Description: Memory Notebook of Nursing Vol. Participants (N 21 Mage 21.0 years) completed two laboratory visits, involving 30 min of exposure to either hypoxia (FIO2 0.12) or normoxia (FIO2 0.21). delayed) being the independent variables. Our data suggest that the association between hypoxemia and cognition may not straightforward. 1 Table of Content PDF Myocardial Infarction Heart Failure 38 (21) 14K views 6 pages Memory Notebook of Nursing Vol. Methods: A within-subjects, counterbalanced experimental design was employed, with condition (hypoxia vs. These preliminary findings are discussed in the context of basic science literature on the protective effects of adaptation to intermittent hypoxemia. In our carefully matched sample, we observed an unexpected advantage of higher hypoxemia on memory. This study is one of the first to compare the cognitive performance of patients with high and low hypoxemia after controlling for demographic factors and aspects of OSA severity that could confound the relationship. No group differences were observed on other neuropsychological measures. Methods: A within-subjects, counterbalanced experimental design was employed, with condition (hypoxia vs. No studies, to date, have evaluated the effects of acute hypoxia exposure on memory interference, which was the purpose of this experiment. The high hypoxemia group performed significantly better on immediate recall (Hopkins Verbal Learning Test - Revised t = -2.50, p < 0.02) than the low hypoxemia group. Purpose: Previous research has evaluated the effects of acute hypoxia exposure on cognitive function, notably executive function. We compared patients with high and low hypoxemia on measures of memory, attention, executive functioning, and motor coordination using independent sample t-tests. Participants completed polysonmography and cognitive assessment. ![]() ![]() The groups differed on severity of hypoxemia but not other demographic (e.g., age, gender, education, estimated premorbid IQ) or clinical (e.g., sleep related respiratory disturbances, daytime sleepiness, depressive symptoms) variables. Two groups of 20 patients with newly diagnosed OSA were compared. The goal of the current study was to isolate the contribution of hypoxemia to cognitive impairment in OSA. Attempts to understand the causes of cognitive impairment in obstructive sleep apnea (OSA) are complicated by the overlap among clinical and demographic factors that may impact cognition.
0 Comments
Leave a Reply. |